"Positive pressure irrigation (SinuPulse Elite®) retains a larger volume of solution and irrigated the sinuses more consistently than other methods. Positive pressure irrigation distributes saline solution reliably to the ethmoid and maxillary sinuses and is distributed to the bilateral maxillary sinuses in the majority of all subjects."

"Negative pressure irrigation (inhaled or "sniffed" saline)  Negative pressure irrigation is the simplest least expensive irrigation method and is maintenance free, However, delivery with this method is difficult to control and has the disadvantage of preferentially irrigating the side of the nasal cavity. It tends to irrigate one maxillary sinus or the other but not both."

"Nebulizer: The system uses technology previously applied to oral nebulizing devices for delivery of drugs to the bronchopulmonary system.  It is comfortable and easy to use but is expensive, time intensive requiring nearly 10 minutes per treatment.  Of the three treatment methods, the nebulizer gave the poorest results. Saline distribution was the lowest and the nebulizer method did not distribute the solution reliably."